drug log

log #003: 7-OH

background

7-hydroxymitragynine (7-OH) is a terpenoid indole alkaloid (this is a fancy way of saying "naturally-occurring compound") from the plant mitragyna speciosa, commonly known as kratom.

it was first described in 1994. it is a human metabolite metabolized from the mitragynine** _{(mitragynine is an indole-based alkaloid. it's one of the main psychoactive constituents in kratom. it's an opioid known for its pain-relieving and euphoric effects.)} present in kratom. 7-oh exhibits significantly higher binding affinity to mu-opioid receptors (MOR) than morphine, with estimates ranging from 14 to 22 times greater potency. it demonstrates opioid-like effects and can substitute for morphine in a dose-dependent manner.

recent developments in the market have introduced semi-synthetic 7-OH products, which differ from traditional kratom preparations in both concentration and route of administration. products often contain up to 98% 7-OH and are marketed in formulations such as sublingual tablets/strips or also powders. some of these formulations bypass first-pass metabolism, significantly increasing bioavailability and potentially amplifying their opioid-like effects.

acquisition

i live in the united states. i did a few days of research and bought 40 12mg 7oh tablets from an in-state online vendor. 20 blue raspberry flavored tablets, 20 unflavored. i placed my order on a wednesday night and they were at my door 2 days later.

i have never tried opiates before. my boyfriend, who's been clean for 3 or so years, told me never to touch them. i know you must be screaming, "why develop an opioid addiction if you're not already hooked on them?!". listen.

while researching, i found that low doses of 7oh specifically (idk about other opioids like heroin or percs) provide stimulating effects. i love stimulants. i have depression and autism, i hate depressants. i need all the energy i can get. i have that kind of internal drive that makes me feel like shit if i don't do something productive every day.

administration

full transparency: i'm on 100mg of sertraline (zoloft). i was out with friends before i tried 7oh. i had a bit of alcohol and one hit of a thc vape. about an hour later, i went home.

i cut a single blue raspberry 12mg tab into fourths. i put a fourth (about 3mg) under my tongue and let it dissolve. it tasted like blue raspberry candy, though there was a chemical-y aftertaste that i can't describe.

the high

i wasn't feeling anything after 30 mins so i took another 3mg sublingually. about 30 minutes later, i closed my eyes and started experiencing a full-body high. there was this tickling warmth blooming from the center of my chest in time with my breathing. it felt "good" to breathe. my muscles were relaxed. my sheets felt cool on my skin. i checked my pupils in the mirror and they were dilated. i thought that was interesting because opiates usually constrict the pupils.

i fell asleep and slept for 2 hours. i woke up around 2am and took another half (about 6mg) sublingually. i came up and stayed awake for about 2 hours. i wasn't "energized", but i spent the time fixating on 7oh research. the best way i can describe it is having the mind of low-dose adderall with the body of low-dose morphine.

i don't remember this next part at all. according to the log i kept in my phone, i woke up at 7:30am and took an entire 12mg tab. 30 minutes later, i felt sleepy but not much else.

yknow that pressure you get in your ears when you yawn? i kept experiencing that. it was comforting at first when i was snuggled up in bed, but it kept happening with the smallest movements of my head. it started to annoy me. i googled it and found out that opiates are ototoxic (meaning toxic to the ear, auditory nerve, and/or vestibular system). i was more annoyed than worried.

i experienced in-ear pressure every few minutes then nodded out into a nap. i woke up around 4 hours later. that didn't last long, though. i ate, pissed, drank some water then crawled back into bed. i slept the rest of the day and the entire night. i woke up the next day around 7:30am (i wonder if i woke up that early because my body was craving another dose?).

the good

- the warmth in my chest made it feel "good" to breathe. i kept taking deep, slow breaths. i just can't explain it. it felt so good lol

- i get nightmares every (sober) night. under 7oh, i had pleasant dreams. i can't remember them now, but i think i had a dream that i was in an art museum. on display were works by dick bruna, takeuchi naoko and jim henson. what a random lineup. i wonder what they have in common.

- the method of administration. a sublingual pill is much easier than shooting up.

the bad

- the itch. itching is a common side effect of opiates. being autistic, i have a slew of other medical problems. fortunately, i'm on antihistamines for one of these problems, so the itching i experienced under 7oh was minimal. i have no scratches, welts, hives, etc. i remember nodding in and out of consciousness while laying on my back, idly scratching my chest, stomach and hips. the itching was mild and i could sleep through the night.

- lip and tongue staining. since the tabs i ate were blue raspberry-flavored, my tongue and lips were stained blue. the lip stain went away after scrubbing with water for a bit. idk about the tongue stain because i didn't bother hiding it. i live with other people but i don't make it a habit of showing them my tongue.

- the knockout. i slept my entire saturday away :/

closing thoughts

i'd like to try 7oh again when i'm completely sober. i wasn't trashed but i had some alcohol and thc in me, which might've contributed to the sedating effects i experienced. i'm dying to experience that stimulant effect!! i really hope that's possible because if not, then i have a stash of pills that i don't even like...

r8 the stash